Sickle cell anemia

Source:  Sickle cell anemia    Tag:  phenotype of sickle cell anemia




Sickle cell anemia is an inherited blood disease. It is particularly common in populations from sub-Saharan Africa, the Caribbean, India, the Middle East and the Mediterranean basin.

The characteristics of the different levels of the phenotype of sickle cell disease are:

- At the organic level : severe anemia, weakness, respiratory disorders, heart attack and blood (blood circulation is Unusual).

- At the cellular level: the low number of red blood cells, Change its shape (crescent, or sickle), this latter leads to the blockage of blood vessels and thus non saturate tissue of blood

- At the molecular level : Hemoglobin in the lack of oxygen is less soluble, forming a solid grid of fibers in the cytoplasm of erythrocytes.