let us fight against deadly disease--Thalassaemia

Source:  let us fight against deadly disease--Thalassaemia    Tag:  origin of thalassemia
---------- Forwarded message ----------
From: Ranganath Daruri <[email protected]>
Date: 2011/5/6

Dear All,

ON SUNDAY 8th may 2011    7-15 AM TO 11AM  MANY ACTIVITIES ARE HAPPENING FOR AWARENESS ABOUT THALASSAEMIA PREVENTION.

LET'S JOIN OUR HANDS TO FIGHT AGAINST TAHALASSAEMIA.

Please let me know if any one wish to join.

Contact :
Manoj M-9885613697
Ranganath D 9885613697
Pavan : 9030001950

Venue:
Necklase Road –Eatstreet.
Time:7am-11am
Contact:

What is Thalassaemia
  • It  occurs because of defect in hemoglobin molecule.
  • The production of hemoglobin in the molecule will be partly or completely stopped.
  • Thalassaemia is an inherited disorder of the red blood cells.
  • Thalassaemia Carrier: one of the two chromosomes of the cell are infected.
  • Thalassaemia Major: two chromosomes are infected , basically It happends when both parents are Thalassaemia Carriers.
  • This disease carries from parents to children because of the two infected chromosomes

THALASSAEMIA CARRIES AND DANGEROUS WHEN MARRIAGES BETWEEN TWO THALASSAEMIA CARRIERS.




Reduction of Thalassaemia Majors by marriage between Thalassaemia Carrier and Healthy Person




Types of Thalassaemia

There are three types of thalassemia that are of global importance:
  1. Alpha (α) - thalassaemia
  2. Beta   (β) - thalassaemia
  3. Haemoglobin E (HbE)  thalassaemia

Epidemiology of Thalassaemia
                                         
It is estimated that there are 80-90 million carriers of Thalassaemia worldwide and 60-70000 births of affected children every year. Most of these die in early life, often without a diagnosis or because of inadequate treatment

l  People of Arab origin are over 3% carriers. In Central Asia 4-10% and in South East Asia, the Indian subcontinent and China 1-40% carriers (the very high rates in this part of the world are due to HbE).  

It is estimated that there are 35 million carries of Thalassemia i.e. 1 in 25. Around 10 – 15,000 babies with Haemoglobinopathies are born in India every year. Few of the ethnic group like Sindhis, Gujarathis, Punjabis, Jains, Marwadis, etc is high risk communities for this disease

Signs and Symptoms

The child is normal at birth but between the age of 6 weeks and 2 years

parent or doctors can identify important signs like pale skin, restlessness, poor appetite and a mass (spleen) felt on the left side of the tummy.


Diagnosis

Patient subjected to special tests like Hb Electrophoresis (estimation of HbA2 and Hb F levels) and complete blood picture (CBP) will clinch the diagnosis. 


  Cost of Treatment
           

Cost of the Treatment

Particulars
Cost
1
Blood transfusion
Free*
2
Leucodepletion filters (per transfusion)
Rs. 1,000/-
3
Iron Chelation

a)
Desferal (Parental Chelation


i.  Infusion pump (once in life time)
Rs. 14,040/-

ii. Drugs (life long)
Rs. 8,000 to 10,000 / month
b)
Kelfer (Oral Chelation)


i. Drugs (life long)
Rs. 2,000 to 3,000 / month
c)
Tab. Asunra 400mg & 100mg
Rs.2300 to 9000 per month
4
Other drugs and disposables (life long)
Rs. 500 to 1,000 / month
5
Periodic medical check-up (life long)
Rs. 2,000 / year
6
Bone marrow transplantation (permanent cure)
Rs. 10,00,000/-


Regards
Ranganath Daruri
9885613697